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However, this treatment may not be practical because harvesting skeletal muscle may lead to significant muscle loss and increased susceptibility to infection.
One effective way to develop the needed tissue is through tissue engineering. Tissue engineering is the development of molecules, cells, tissues, or organs to replace or support dysfunctional body parts. Myoblasts, which are muscle precursor cells, a form on stem cells found in muscle, are a promising cell source for tissue engineering because they play an active role in regenerating muscle due to injury. Normally quiescent, myoblasts respond to muscle injury by rapidly proliferating and then differentiating, which results in the fusion of neighboring myoblasts into myofibers...
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