Does An Aspirin A Day Take The Gi Benefit Of A Coxib Away
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Title: Does An Aspirin A Day Take The Gi Benefit Of A Coxib Away

Essay Details:

Subject: Technology
Author: Jerry T
Date: April 26, 2012
Level: University
Grade: B
Length: 2 / 330

Essay text:

Moreover, because coxibs were heralded as having an improved safety profile owing to fewer toxic GI effects compared with traditional NSAIDs, the potential loss of this protection in the setting of the use of dual COX inhibitors, such as aspirin or over-the-counter NSAIDs, may not be appreciated by clinicians prescribing these agents. GI Effects of Aspirin in Those Receiving Coxib vs Traditional NSAID Therapy While no controlled clinical outcome studies have yet to be performed specifically to assess GI risk among those receiving aspirin in combination with a coxib or traditional NSAID, mounting evidence gleaned from subanalyses of efficacy and safety trials suggests that there are very few data to establish a GI safety advantage with coxibs vs traditional NSAID therapy in the setting of aspirin cotherapy...

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