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The test can only be done between 15 and 20 weeks of pregnancy. It is very important to understand that Maternal Serum Screening is not a diagnostic test, and can only indicate if a pregnancy is at increased or decreased risk for any of the above conditions. Women who are found to be at increased risk are offered further diagnostic testing such as detailed ultrasound and/or amniocentesis. Not all affected pregnancies are detected by the MSS. MSS can detect approximately 75% of cases of Down Syndrome, 85% of Open Spina Bifida and 60% of Trisomy 18. The test is relatively painless and poses no risk to the mother or the pregnancy...
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