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In 1964, Melmon and Rosen summarized all knowledge
of the disease and coined the name "Von Hippel-Lindau." The invention of ultrasound aided detection in the late 1970's, and by the mid 1980's, MRI was commonly used for detection of angiomas on the spine. In 1993, the VHL gene was located by researchers at the National Cancer Institute.
Patients with VHL suffer tumors known as angiomas (they are referred to as hemangioblastomas when discussing the retina, brain, or spinal chord and pheochromocytomas when discussing the adrenal glands) consisting of tiny knots of blood vessels. These angiomas can occur in the brain, spinal cord, retina, adrenal glands, kidney, pancreas, and very rarely in the epididymis is men and the fallopian tubes in women...
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Common topics in this essay:
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