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Obesity thus contributes to premature mortality. Of all obesity-related diseases, noninsulin dependent diabetes is most clearly and strongly associated with obesity.
Obesity is associated with too many adipose cells (hyperplastic obesity), adipose cells that are too large (hypertrophic obesity), or both. While changes in the size of adipose cells may occur at any age, the number of adult cells are fixed and determined by weight gain during certain periods of childhood development; fat cell numbers are established by late adolescence and, once established, does not decline.
Women generally have more subcutaneous fat than men, but men appear to suffer a greater cardiovascular risk from a given degree of fat than women...
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