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There is an increasing concern that HEV acts as a possible zoonotic agent between certain animals and humans. There is also evidence that humans can be infected with divergent HEV strains which shows the possibility of the emergence and evolution of new HEV strains.
Introduction
As mentioned in the abstract, HEV virions are small, non-enveloped 32-34nm diameter particle with isosahedral symmetry. The viral genome is approximately 7.5kb in length and is a single stranded, positive-sense, polyadenylated RNA molecule that contains short 5' and 3' non-coding regions of 27 and 68 nucleotides respectively...
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