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Title: 5s

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Subject: Business
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Date: June 29, 1997
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Length: 11 / 3036
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Laboratory has successfully applied SPR with colloidal gold particles in buffered solutions. This application offers many advantages over conventional SPR. The support is cheap, easily synthesized, and can be coated with various proteins or protein ligand complexes by charge adsorption...

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With colloidal gold, the SPR phenomenon can be monitored in any UV spectrophotometer. For high throughput applications we have adapted the technology in an automated clinical chemistry analyzer. This simple technology finds application in label free quantitative immunoassay techniques for proteins and small analytes, in conformational studies with proteins as well as real time association dissociation measurements of receptor ligand interactions for high throughput screening and lead optimization...

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