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Title: - Investigation of the role of MicroRNA- 223, MicroRNA -381 and MicroRNA- 505 in the regulation of transcription factor NFI-A.

Essay Details

Subject: Science
Author: Kay F
Date: June 30, 2015
Level: University
Grade: A
Length: 7 / 1981
No of views: 0
Essay rating: good 0, average 0, bad 0 (total score: 0)

Essay text:

It has also been shown to play a role in preconditioning-induced neuroprotective functions (Zheng et al, submitted). Experiments have indicated that human NFIA is negatively controlled by miR-223, in that its translation is repressed by the binding of micro RNA 223 to a binding site on the 3’ UTR of the gene...

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(Fazi et al,2005). MicroRNAs (miRNAs) are endogenously encoded, 22 nucleotide small noncoding RNAs that have been found to direct sequence specific down regulation by mRNA cleavage, cleavage-independent mRNA degradation or translational suppression of mRNA. (Pillai,2005 ; Valencia-Sanchez et al, 2006)...

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