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Title: Simvastatin
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Science |
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| Date: |
July 27, 1999 |
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| Length: |
5 / 1242 |
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Essay text:
Further analysis lead to the discovery of a new compound now known as Mevastatin.
By 1976, the drug company Merck & Co. had become involved in the development of statins, and referencing Drs. Endo and Kuroda’s research, managed to successfully isolate a similar molecule, Lovastatin, from Aspergillus terreus... Showed first 250 characters
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Endo and Kuroda’s research, managed to successfully isolate a similar molecule, Lovastatin, from Aspergillus terreus. The new compound was slightly more effective as an HMG Co-A reductase inhibitor than mevastatin. By altering the chemical composition of the mevastatin molecule, various statin drugs were later created... Showed next 250 characters
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