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The overall reaction can be expressed this way:
Glucose + 2 NAD+ + 2 ATP + 2 Pi ?u 2 NADH + 2 pyruvate + 4 ATP + 2 H2O + 4 H+
The individual steps of the conversion of glucose into pyruvate are (in brief):
A glucose molecule from the hydrolysis of starch or glycogen is phosphorylated using one ATP molecule to give glucose-6-phosphate.
The glucose-6-phosphate is converted to fructose-6-phosphate by isomerisation.
Fructose-6-phosphate is again phosphorylated to give fructose-1,6-diphosphate with the use of another ATP molecule.
Next, the fructose-1,6-diphosphate is then lysed into two molecules of 3-carbon sugar (dihydroxyacetone phosphate and glyceraldehyde-3-phosphate) which are interconvertible...
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