Biology
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Title: Biology

Essay Details:

Subject: Technology
Author: Tony G
Date: June 23, 2010
Level: University
Grade: A
Length: 3 / 703

Essay text:

But because of issues with stereochemistry, chemists are currently limited to extending peptides from the nitrogen end. "This is such a profound problem that the impossibility of synthesising peptides from the acid terminus has become dogma in the field" - Lawrence Harwood 'Conventional peptide synthesis is always carried out in a very linear manner, building the peptide chain from the nitrogen terminus, as attempts to grow peptide chains from the acid terminus result in scrambling of the stereochemistry,' explains Harwood. 'This is such a profound problem that the impossibility of synthesising peptides from the acid terminus has become dogma in the field of peptide synthesis...

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