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Thus the first patients were treated at the National Institutes of Health (NIH) in Bethesda, Maryland. Two years after receiving their last infusions of generally altered cells to boost their weakened immune systems; the first patients ever to undergo gene therapy are still healthy and benefiting from the treatment. According to a historic research paper published in Science on October 19, 1995, the two girls still have white blood cells bearing copies of the replacement ADA gene. Patient One, whose health improved significantly following gene therapy, has maintained a normal white blood cell count as well as measurable levels of the ADA enzyme, which was almost nonexistent prior to the treatment...
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